Systemic lupus erythematosus (SLE) – is a serious systemic disease of the connective tissue of the immune nature with which are surprised the skin and various internal organs.
90% of patients are women aged 20-40 years. The prevalence of the disease among different races and ethnic groups is not the same: SLE often occurs in blacks and whites less often. The disease has a a chronic character with periods of exacerbation and requires prolonged anti-inflammatory therapy.
The disease is a chronic autoimmune inflammation associated with production by cells of immune system antibodies against of the cell DNA own body. These antibodies destroy the cells of the connective tissue of various organs and systems (skin, kidneys, nervous system, blood vessels, blood cells, heart, lungs, gastrointestinal tract, eyes), which causes many clinical manifestations of Systemic lupus erythematosus.
Symptoms of lupus
Systemic lupus erythematosus may begin with the destruction of any single organ or several at once. Depending on this, the primary will appear certain symptoms of the disease:
– Pain in the muscles and joints;
– Swelling of the hands and feet associated with arthritis of small joints;
– A rash on the cheeks and bridge of the nose;
– Discoid lupus thick red scaly patches on the scalp, ears, face, hands, open areas of the chest and back;
– Patchy hair loss;
– Sores on the mucous membrane of the mouth and nose;
– Increased sensitivity of the skin to sunlight;
– Depression, anxiety disorders, psychosis;
– Nausea, diarrhea;
– Reduction of view.
– Rises in temperature, weakness, headaches, fatigue.
Treatment of lupus
If you notice in yourself or your loved ones symptoms of SLE try as soon as possible address to the therapist. Upon confirmation of the diagnosis should be be attentive to prescribing physician and monitor their own health.
In patients with SLE exist a peculiarities of pregnancy and childbirth. So if you already have a diagnosis of SLE, and you’re going to conceive a child, be sure to consult with your doctor.
The goal of therapy is struggle against severe exacerbations and maintaining a satisfactory condition of the patient during remission. The basis of treatment is anti-inflammatory drugs (nonsteroidal antiinflammatory drugs, corticosteroids) and cytostatic immunosuppressants. Depending on the clinical manifestations is
performed symptomatic therapy. In some cases, is shown extracorporeal detoxification (plasmapheresis, hemosorbtion, cryoplasmasorption).